Mild Microglial Responses in the Cortex and Perivascular Macrophage Infiltration in Subcortical White Matter in Dogs with Age-Related Dementia Modelling Prodromal Alzheimer's Disease.

In the CCD dogs, the difference in %Aβ area between grey matter and white matter was marginally significant ( p = 0.05, Mann-Whitney) ( Table 2 ), thereby supporting the finding of the Aβ plaques being primarily present in the grey matter, and especially in the deep cortical layer V and VI.

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