cholerae O139 and O1 are identical, but that there is no evident cross protection of O1 versus O139 cholera, suggests that even if core-specific antibodies do contribute some degree of protection, they are not clinically highly significant.
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Defining Polysaccharide-Specific Antibody Targets against Vibrio cholerae O139 in Humans following O139 Cholera and following Vaccination with a Commercial Bivalent Oral Cholera Vaccine, and Evaluation of Conjugate Vaccines Targeting O139.
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