Localized and Systemic Inflammatory Mediators in a Murine Acute Mastitis Model.

In supporting increased oxidative stress in LPS-treated glands, the activities of the antioxidant enzymes CAT and SOD were decreased in the mammary tissue and/or plasma after LPS treatment in this study, consistent with a decreasing trend in total antioxidant capacity observed in LPS-treated mammary glands at 12 and 24 h in our previous study. 16 One of the top DEGs is the overexpression of Klk10 , which encode a serine protease, consistent with the findings in cows. 48 This finding is of particular interest because a modification o

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