Diclofenac toxicity in susceptible bird species results from a combination of reduced glomerular filtration and plasma flow with subsequent renal tubular necrosis.

PeerJ · 2021 · PMC8388555 · PMID 34513332

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almost insignificantno p-value reported

With IOH clearance being constantly decreased in all the chickens, and PAH clearance being almost insignificant in only the two chickens that died (Tm PAH and Cl UA both reduced by more than 98%, furthermore with Tm uricacid being absent), it appears that tubular excretion of uric acid was affected.

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