Final data from this phase II clinical trial reported a positive trend in mean overall survival (mOS) for patients treated with neoadjuvant GVAX alone (35.0 months compared to 24.8 months in historical controls) in comparison with patients who were additionally treated with cyclophosphamide (mOS 15.4 and 16.5 months) [ 29 ].
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Challenges and Future Perspectives of Immunotherapy in Pancreatic Cancer.
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