Barely Significant
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Integral Membrane Protein 2A Is a Negative Regulator of Canonical and Non-Canonical Hedgehog Signalling.

Cells · 2021 · PMC8394137 · PMID 34440772

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hedged sentence
0.0000
closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp = 1 × 10 −16actually significant
STRING analysis reveals a highly significant clustering ( p = 1 × 10 −16 ) of over 90% of the proteins identified ( Figure 7 ), with the existence of sub-clusters related to ER protein quality control, mitochondria membrane protein translocation, nuclear import, and stress granules.

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