What can we learn from β-cell failure biomarker application in diabetes in childhood? A systematic review.

World J Diabetes · 2021 · PMC8394223 · PMID 34512897

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Their most relevant finding was the significant increase of several proinflammatory cytokines and chemokines like IL-15, IL-8, IL-17F, IP-10 and MIP-1β in CD patients and its highly significant correlation with the grade of small bowel mucosa atrophy, which plays a major role as a sign of small bowel mucosa inflammation and damage.

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