The studies were of moderate quality and showed either no effect of vitamin C or a positive trend, although this has rarely been statistically proven in group comparisons.
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Clinical efficacy and safety of oral and intravenous vitamin C use in patients with malignant diseases.
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Yet, a late large cohort study with patients with breast cancer reported a highly significant worse outcome for patients taking supplements with antioxidants during radio- or chemotherapy (Jung et al. 2019 ).