Effective Osteogenic Priming of Mesenchymal Stem Cells through LNA-ASOs-Mediated <i>Sfrp1</i> Gene Silencing.

Pharmaceutics · 2021 · PMC8398380 · PMID 34452242

Europe PMC DOI

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highly significantno p-value reported

Whereas the osteogenic induction using the previous method was highly significant, the overall increase in bone formation in vivo through the silencing of Smurf1 in MSCs did not exceed 30%.

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