A CTC count of ≥2 was significantly associated with an increased risk of progression and death in the univariate analysis, but the association was borderline significant in the multivariate analysis when the established prognostic factors—platinum-free interval, CA-125 level, number and size of tumor foci, tumor grade and ECOG overall performance status—were considered.
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The Detection of Stem-Like Circulating Tumor Cells Could Increase the Clinical Applicability of Liquid Biopsy in Ovarian Cancer.
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