Barely Significant
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Uptake of bilateral-risk-reducing-mastectomy: Prospective analysis of 7195 women at high-risk of breast cancer.

Breast · 2021 · PMC8406355 · PMID 34464846

Europe PMCDOI
1
hedged sentence
0.0770
closest p · 1.5× alpha
0.0770
boldest claim

The sentences

of borderline significancep = 0.077so close (0.05 < p ≤ 0.1)
For BRCA1/2 carriers uptake was higher in those with known PVs in their family at entry, 138/316 (43.7%) versus 55/163 (33.7%)-p = 0.04 those found later: 10-year uptake 47.5% (95%CI = 41.7–53.8) versus 39.4% (95%CI = 31.4–48.6) in those with PVs found later (OR = 1.2; 95%CI = 0.9–1.6)- Supplementary-table-4 , this was of borderline significance for BRCA1 (OR = 1.6; 95%CI = 0.99–2.4); p = 0.077 supplementary-figure-2 ).

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