Chromosome-scale assembly and evolution of the tetraploid Salvia splendens (Lamiaceae) genome.

Furthermore, although marginally significant, TE-mediated epigenetic silencing might lead to the repression of gene expression for the dominant subgenome in S. splendens (SAyes_SBno in Fig. 3b ) 52 .

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However, although polyploidization may be significant in increasing genetic variation and affecting gene expression, we still have a limited understanding of the full extent of whether homoeologs resemble or differ from each other in their expression patterns, the spatiotemporal dynamics of these relationships, and how genomic rearrangement, transposable element (TE) proliferation, and sequence diversification impact these differences.

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