FCM analyses indicated that the absolute numbers of infiltrated OT‐I cells were significantly decreased in the mice receiving additional purified exosomes, whereas OT‐I cells showed an increasing trend after anti‐PD‐L1 pretreatment (Figure 4F ).
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PDL1-positive exosomes suppress antitumor immunity by inducing tumor-specific CD8<sup>+</sup> T cell exhaustion during metastasis.
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