Immunofibrotic drivers of impaired lung function in postacute sequelae of SARS-CoV-2 infection.

JCI Insight · 2021 · PMC8410030 · PMID 34111030

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highly significantno p-value reported

Confirmation of the relationship between LCN2, MMP-7, and HGF and pulmonary function using simple linear regression identified a highly significant, inverse correlation with FVC and DLCO ( Figure 5, B and C ).

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a statistical trendno p-value reported

Plasma levels of LCN2 and MMP-7 were significantly higher in the validation ICU group compared with the validation home group, whereas a statistical trend was observed for HGF ( Supplemental Figure 4A ).

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