marginally significantP < 0.05
Using significant meQTLs on chromosome 1, analyses using only African American samples ( N = 112) showed that 99.91% of the meQTLs were directionally consistent with the full analysis, with 92% marginally significant ( P < 0.05) and 66% genome-wide significant (FDR < 0.01) in the smaller sample size and an overall sharing of π 1 = 0.995.