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Differential Roles of Actin Crosslinking Proteins Filamin and α-Actinin in Shear Flow-Induced Migration of <i>Dictyostelium discoideum</i>.

Front Cell Dev Biol · 2021 · PMC8415421 · PMID 34485315

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However, at the lower shear stress of 23 dyn/cm 2 the initial response of overexpressors at 6 s post-stimulation was slightly stronger compared to cells with endogenous levels of ddFLN, although this difference did not quite reach statistical significance (0.10 ± 0.02 vs. 0.15 ± 0.02 response over basal for wild-type vs. overexpressor cells, respectively; mean ± SE; P = 0.05; Figures 4B,C ).

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