Evaluation of the Impact of Intratumoral Heterogeneity of Esophageal Cancer on Pathological Diagnosis and P16 Methylation and the Representativity of Endoscopic Biopsy.

Front Oncol · 2021 · PMC8416173 · PMID 34485122

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a decreasing trendno p-value reported

In “1–5 cm” subgroups, 91.7%, 50.0%, 50.0%, 30.0%, and 25.0% biopsies were P16 methylation positive, respectively, showing a decreasing trend with the increase in the distance from the biopsy site to the tumor mass/lesion ( p trend <0.05).

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