Barely Significant
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Angiopoietin-like protein 4 (ANGPTL4) is an inhibitor of endothelial lipase (EL) while the ANGPTL4/8 complex has reduced EL-inhibitory activity.

Heliyon · 2021 · PMC8417300 · PMID 34504977

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did not achieve significanceno p-value reported
In the case of ANGPTL3/8, the inverse correlation with HDL did not achieve significance, while the correlation of ANGPTL4/8 with HDL was statistically significant. 3.2.

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