SARS-CoV-2 sculpts the immune system to induce sustained virus-specific naïve-like and memory B-cell responses.

Using conventional gating strategies (Supplementary figure 2 a) and pairwise longitudinal comparisons, we identified an increased proportion of immature CD21 low transitional B cells (Figure 2k ) and a highly significant transient expansion of naïve B cells during the acute phase of infection (Figure 2l ).

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