Humoral response to neurofilaments and dipeptide repeats in ALS progression.

Ann Clin Transl Neurol · 2021 · PMC8419401 · PMID 34318620

Europe PMC DOI

hedged sentence

0.0680

closest p · 1.4× alpha

0.0680

boldest claim

The sentences

close to significancep = 0.068so close (0.05 < p ≤ 0.1)

Adding Nf‐H and Nf‐L protein concentrations above the median to the multivariate prognostic model showed that higher levels of these analytes had a mild but significant effect on survival only for Nf‐H (HR: 1.728, CI: 1.026–2.909, p = 0.040), while Nf‐L protein concentration effect was only close to significance (HR: 1.921, CI: 0.986–4.056, p = 0.068; Fig. 4E and F ).

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