Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection.

However, a large fraction, if not a majority, of actionable cancer DNA alterations reported to date were done so using short-read technologies and are therefore are single-base mutations [ 13 ], and in tumor tissue samples, there may be significant cancer heterogeneity and/or low tumor fraction.

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