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Effects of N-Methyl-D-aspartate receptor (NMDAR) and Ca<sup>2+</sup>/calmodulin-dependent protein kinase IIα (CaMKIIα) on learning and memory impairment in depressed rats with different charge by modified electroconvulsive shock.

Ann Transl Med · 2021 · PMC8422109 · PMID 34532457

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a decreasing trendno p-value reported
In this study, we found that with higher electric charge, the combined amount of the 2 decreases, and the expression levels of GluN1 and GluN2B in the hippocampus show a decreasing trend, while GluN2A/GluN2B ratio only increases significantly under the condition of high stimulation electricity.

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