Cognitive Trajectories and Dementia Risk: A Comparison of Two Cognitive Reserve Measures.

Front Aging Neurosci · 2021 · PMC8424183 · PMID 34512313

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0.0590

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

marginally statistically significantp = 0.059so close (0.05 < p ≤ 0.1)

We found a statistically significant interaction among continuous residual-based CR and brain-integrity index over time (β = –0.011; p < 0.05), as well as a marginally statistically significant interaction among the top tertile of residual-based CR, brain-integrity index, and time (β = –0.021; p = 0.059; reference: low reserve × brain integrity × time).

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marginally significantp = 0.06so close (0.05 < p ≤ 0.1)

In the modulation analysis using MMSE as outcome ( Supplementary Table 2 and Supplementary Figure 4 ), a three-way interaction residual-based CR × brain-integrity-index × time was statistically significant using continuous operationalization ( p < 0.05), and marginally significant using categorical operationalization ( p = 0.06 for the middle tertile and p = 0.09 for the top tertile).

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