Treatment patterns in rheumatoid arthritis patients newly initiated on biologic and conventional synthetic disease-modifying antirheumatic drug therapy and enrolled in a North American clinical registry.

The other biologic monotherapy cohort seemed to show an increasing trend over the 2004–2007, 2008–2011, and 2012–2015 time periods (28.6%, 36.6%, and 42.0%, respectively).

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There was a decreasing trend of restarting index therapy over time in the Corrona RA registry across the treatments, with 1.7–3.3% of patients restarting index therapy in the 2012–2015 period.

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