We validated some of the RNA-seq results by qPCR in ADAR1 -knockdown Cal62 cells; specifically, the highly significant candidate genes related to the aforementioned processes of cell cycle, extracellular organization, transcription regulation and apoptosis (Fig. 1 C).
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An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks.
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