Safety Warning for ChAdOx1 nCov-19 Vaccine in Patients with Sickle Cell Disease.

Mediterr J Hematol Infect Dis · 2021 · PMC8425344 · PMID 34527211

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possibly significantno p-value reported

It was characterized by severe back pain, a significant drop in hemoglobin, platelets, and a statistically significant rise in liver enzymes, in particular, ALP in all the three cases (P-value < 0.05), denoting possibly significant bone infarction (most likely spinal, given the persistent back pain).

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