Statistical evaluation by the STRING webtool detected a highly significant enrichment of diverse pathways and compartments ( Suppl.
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Increased presence of nuclear DNAJA3 and upregulation of cytosolic STAT1 and of nucleic acid sensors trigger innate immunity in the ClpP-null mouse.
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The main IFN-I transcripts, Ifna1 and Ifnb1 , showed only partially significant inductions ( Figure S2a ).