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Genomic instability in lower-grade glioma: Prediction of prognosis based on lncRNA and immune infiltration.

Mol Ther Oncolytics · 2021 · PMC8430277 · PMID 34553030

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Genomic instability (GI), as a ubiquitous characteristic of human cancers, represents an elevated trend of acquiring new mutations in the genome, thereby driving tumor progression and resistance to therapy. 6 Previous studies have shown that higher GI is associated with worse prognosis for several cancer types, such as ovarian, colorectal, and breast cancers. 7 , 8 , 9 , 10 On the other hand, GI driv

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