Deregulated Expression of Immune Checkpoints on Circulating CD4 T Cells May Complicate Clinical Outcome and Response to Treatment with Checkpoint Inhibitors in Multiple Myeloma Patients.

Int J Mol Sci · 2021 · PMC8431347 · PMID 34502204

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

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boldest claim

The sentences

of borderline significancep = 0.06so close (0.05 < p ≤ 0.1)

While we noted an increased proportion of CD4 + CD69 + T cells in the PB of all patients (as shown in Table 1 ), a statistically significant difference was found only between the RRMM group and healthy controls ( p = 0.027); in the newly diagnosed (NDMM) group, the increase in CD69 + cell expansion was of borderline significance ( p = 0.06).

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