TNF-α and IFN-γ Participate in Improving the Immunoregulatory Capacity of Mesenchymal Stem/Stromal Cells: Importance of Cell-Cell Contact and Extracellular Vesicles.

Int J Mol Sci · 2021 · PMC8431422 · PMID 34502453

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an increasing trendno p-value reported

Stimulation of human BM-MSCs with high concentrations of IFN-γ for 7 and 14 days increases the senescence of these cells, resulting in a lower clonogenic capacity and an increasing trend in the percentage of apoptotic cells [ 165 ].

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