In both MIA-PaCa-2 ( Figures 3 E and 3G) and H23 ( Figures 3 F and 3H) co-culture experiments, Pearson correlation coefficient analysis revealed a highly significant correlation between Cav-1 expression and SSH20, but not SN-38.
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A novel protein-drug conjugate, SSH20, demonstrates significant efficacy in caveolin-1-expressing tumors.
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