Pharmacological inhibition of PAI-1 alleviates cardiopulmonary pathologies induced by exposure to air pollutants PM<sub>2.5</sub>.

Environ Pollut · 2021 · PMC8434953 · PMID 34426376

Europe PMC DOI

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highly significantno p-value reported

This result is highly significant, as it clearly indicates the beneficial effect of PAI-1 inhibitor TM5614 in improving vascular thrombosis, a major pulmonary pathology, in mice exposed to air pollutant PM 2.5 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.