A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.

J Cell Sci · 2021 · PMC8435292 · PMID 34345895

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highly significantno p-value reported

For both genetic backgrounds, the difference between Pkd2 −/poreL1 mice and Pkd2 +/+ mice was statistically highly significant whereas this was not the case for the difference between Pkd2 poreL1/poreL1 mice and Pkd2 +/+ mice ( Fig. 8 C).

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