Notably, an increasing trend was found in Tor1a +/- SPNs LTP, compared with wild-type SPNs, indicating a hyperexcitability (Tor1a +/+ : 148.99 ± 12.17 of pre-HFS; Tor1a +/- : 171.82 ± 18.29 of pre-HFS; P <0.05).
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Inhibition of endoplasmic reticulum stress reverses synaptic plasticity deficits in striatum of DYT1 dystonia mice.
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