DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation.

Nat Commun · 2021 · PMC8437946 · PMID 34518533

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highly significantno p-value reported

We detected highly significant correlations with TP53 , PIK3CA , CDH1, GATA3 , and CBFB SNVs (Fig. 4b ), and to a lesser degree with mutation intra-tumor heterogeneity (Extended Data Fig. 10b ).

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