Evidence-based complementary and alternative medicine bioinformatics approach through network pharmacology and molecular docking to determine the molecular mechanisms of Erjing pill in Alzheimer's disease.

Exp Ther Med · 2021 · PMC8438686 · PMID 34539848

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a decreasing trendno p-value reported

However, when the concentrations of 4',5-dihydroxyflavone, polygonatine A and polygonatine C were >50, 80 and 100 μ M, respectively, the survival rate of PC12 cells exhibited a decreasing trend.

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an increasing trendno p-value reported

Immunohistochemical staining revealed that the amount of D1 receptor in the CA1 area of the mouse exhibited an increasing trend, but there was no significant difference in the expression of D2 receptor, which indicates that the expression of D1 receptor is increased in AD model mice.

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