Pd-Catalyzed Direct Modification of an Anti-Alzheimer's Disease Drug: Synthesis and Biological Evaluation of α-Aryl Donepezil Analogues.

ACS Omega · 2021 · PMC8444293 · PMID 34549134

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extremely significantno p-value reported

2.4 Blood–Brain Barrier Prediction Penetrating the blood–brain barrier (BBB) is extremely significant for anti-AD medicines, and so, the BBB penetration of compounds 1 – 15 was predicted by using Calculate Molecular Properties (Discovery Studio 2020 Client).

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