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Risk factors for esophageal squamous cell carcinoma and its histological precursor lesions in China: a multicenter cross-sectional study.

BMC Cancer · 2021 · PMC8444572 · PMID 34530751

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a decreasing trendno p-value reported
Since the 1980s, the local government has taken significant measures to improve the quality of drinking water, and the incidence and mortality of esophageal cancer displayed a decreasing trend compared with regions where no improvement [ 23 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.