It can be said that adverse effects are barely significant after MSCs administrating encourages to further develop therapy using MSCs or derived from the EVs.
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Extracellular vesicles derived from mesenchymal stem cells as a potential therapeutic agent in acute kidney injury (AKI) in felines: review and perspectives.
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The sentences
This for sure indicates that MSC-EXOs could inhibit the NF-κB pathway, which may be significant during the inflammation development in IRI [ 44 , 57 , 58 ].