Should Deep-Sequenced Amplicons Become the New Gold Standard for Analyzing Malaria Drug Clinical Trials?

Antimicrob Agents Chemother · 2021 · PMC8448141 · PMID 34252299

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The economic cost of reagents and deploying these machines to sub-Saharan Africa and Southeast Asia for use in malaria surveillance is likely to be significant and will necessarily need substantial bioinformatics expertise and special training for sequencing data analysis with existing software (e.g., HaplotypR, SeekDeep, and PASEC) ( 17 , 20 , 23 ), reagent supply, and equipment maintenance.

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