Novel ACE2 protein interactions relevant to COVID-19 predicted by evolutionary rate correlations.

ACE2 also has highly significant ERCs to proteins that do not rank it in their top one percent.

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Our network analysis below (“ERC Reciprocal Rank Networks Implicate Coagulation Pathways and Immunity”) further supports extensive interconnections among ACE2, Clusterin, GPR141, and coagulation pathway proteins, implicating the protein interaction pathway as a possibly significant contributor to disruption of coagulation in COVID-19 disease.

also in 649 other papers