In contrast to Baft3 -/- mice that have non-healing but stable lesions, monocyte-deficient ccr2 -/- mice have highly significant deficiencies in iNOS + cells and succumb to progressive disease at the late stages of infection in otherwise resistant C57BL/6 mice ( 164 , 182 , 184 ).
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The Paradox of a Phagosomal Lifestyle: How Innate Host Cell-<i>Leishmania amazonensis</i> Interactions Lead to a Progressive Chronic Disease.
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