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Sulfonylurea antidiabetics are associated with lower risk of out-of-hospital cardiac arrest: Real-world data from a population-based study.

Br J Clin Pharmacol · 2021 · PMC8453495 · PMID 33896015

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Reduction of OHCA risk compared to glimepiride was found with gliclazide (OR adj 0.5 [95% CI 0.3–0.9]), but not glibenclamide (OR adj 1.3 [95% CI 0.6–2.7]); for tolbutamide, the association with reduced OHCA risk just failed to reach statistical significance (OR adj 0.6 [95% CI 0.3–1.002]).

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