An insertion variant of MGMT disrupts a STAT1 binding site and confers susceptibility to glioma.

Cancer Cell Int · 2021 · PMC8454171 · PMID 34544433

Europe PMC DOI

hedged sentences

0.0880

closest p · 1.8× alpha

0.0880

boldest claim

The sentences

a trend towards significanceP = 0.088so close (0.05 < p ≤ 0.1)

While the positive correlation between the expression of MGMT and STAT1-α in subjects with rs10659396 del/del genotype only showed a trend towards significance (Pearson r = 0.335; P = 0.088) (Fig. 4 b), which might be due to the small sample size within this stratum.

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approached the borderline of significanceno p-value reported

Although the other 3 tag-eQTLs were not found to be significantly associated with glioma susceptibility, one of them rs557311 approached the borderline of significance.

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