The genetics of obesity: from discovery to biology.

Nat Rev Genet · 2022 · PMC8459824 · PMID 34556834

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highly significantno p-value reported

Despite its highly significant and widely replicated association with obesity 120 , the causal variants and/or genes in the FTO locus have not yet been pinpointed with convincing evidence, and the mechanisms by which the locus affects body weight have not been fully elucidated.

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