highly significantP < 0.01
An asterisk (*) and two asterisks (**) indicate significant difference ( P < 0.05) and highly significant difference ( P < 0.01) using Student’s t -tests, respectively.
An asterisk (*) and two asterisks (**) indicate significant difference ( P < 0.05) and highly significant difference ( P < 0.01) using Student’s t -tests, respectively.