DNA polymerase θ promotes CAG•CTG repeat expansions in Huntington's disease via insertion sequences of its catalytic domain.

J Biol Chem · 2021 · PMC8463855 · PMID 34473992

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highly significantno p-value reported

Quantitative analysis shows that this reduction in the hairpin-retained and expanded products in PolθΔi2-catalyzed reactions is highly significant ( Fig. 2 B ).

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