Evidence in disease and non-disease contexts that nonsense mutations cause altered splicing via motif disruption.

Nucleic Acids Res · 2021 · PMC8464065 · PMID 34469537

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantP = 1.662 × 10 –8actually significant

The direction of this enrichment is highly significant ( P = 1.662 × 10 –8 , one-tailed exact binomial test).

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