The Link between Type 2 Diabetes Mellitus and the Polymorphisms of Glutathione-Metabolizing Genes Suggests a New Hypothesis Explaining Disease Initiation and Progression.

A polymorphism rs13041792 of the GSS gene was also associated with disease risk, but at a borderline significance level.

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However, inter-population differences in allele frequencies and linkage disequilibrium between SNPs may be significant factors influencing a replication of marker-disease association in a distinct individual population [ 48 ].

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