Additionally, although generally speaking the reported effect sizes may be significant but relatively moderate, on average, small improvements in individual fitness may nevertheless have significant effects on a population level with regard to the development of severe complications after infection.
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Neutralizing a Springboard for Inflammation: Physical Activity to Control the Immune Network.
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The sentences
This is because on a population scale, relatively small improvements in cardiovascular and respiratory health may have a highly significant effect when it comes to the potential severe complications following (SARS-CoV-2) infection—complications that constitute a significant, global and undeniable strain on healthcare systems.